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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df392ddc89d2c4998e012d160836c543cab7df9a6c92edf5af75fbd640494d0' 
  AND token = 'SYzZ6oQcGxrJpxQCml6tSw4sv+t9vgiL8zd7qaAbuRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}