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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781896fc7c2644bae96aa9571ef2cc8ee5ef85c9cf8eef6d43979986577a1f93' 
  AND token = 'ug/nEfd50+9L7eMLnpbh+t47SGrTn63bsYZofrZzj9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}