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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cb9b213dc5ad117affaa948decbaaed7fdfc841a92376c34e8c357e64a4970' 
  AND token = 'hHQwaday5jEakqcFRDmRK1IKVS7y8dFAXrZ5YLmoDp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}