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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2355f81e4b252ad855567b28bcf3af0ee8542c2ec76f5e60eb06d0c07402674a' 
  AND token = 'FYSiHz2VpKbwckUM/Ch+GTQ9ctzFUL6yb16PkGMVw3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}