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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86e22c8875a2b6f36fef9c27abd0732575d68a2a734c04e68bd0fc23300b44e4' 
  AND token = 'Ulumg8VhkbF4ulGkF4IT+GVtpjXArDemozj6gpyFLOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}