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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9a1726e13ae733b357b8c14f135644ff3eef7a335b0abd2941758aba9ab501' 
  AND token = '0I5u8OJS1ZC2U0R5cNsmZeCSBo/W1MeI2IWa2Z0lplY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}