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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81eb1a158593a31c8ffb8519df8cbb2c524d1d8b263544e9568ce336a80d0288' 
  AND token = 'jyfO82x9CD8fqOmXnYXiGGmC8kAR/O+pkIhdx4rw/Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}