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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52215f96f86cef503abf329140f745f977e7c78174562bc34037528233ef16a' 
  AND token = 'xlLau8bEBIadGkSpVOv+w+H1oe+O/KD2R7xSAk4X3dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}