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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad94c99a15359c4305b2bab62221ffe91729b39ca9f8ce3d62829b4ea735d8f' 
  AND token = 'JCQ7A7PHDvdIg0BjHYfVYD4RH2441EDDTYVQ6CyVDqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}