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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae0758519dcfeffb87646fc51655cb4f1dff1d360e6e61d27a79e7d90bd1c8d' 
  AND token = 'AS+zWy2MgqOM6cg4nbG+C6bh19EgVoT7BjwF/9mw4wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}