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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a95ca642238bb328d7e603cc0a94b1013ca98093e0394150fe01372d65abbb' 
  AND token = 'U2jkv6LRxOLTK53IIsp1BZp2nyk+fzI/2wErmn7Tf6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}