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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdee1d72989c477becf5e7d33d80668173336e1fbd822e130e3355d797a3194b' 
  AND token = 'HeoMqJ4oxyf4V916bR6czpSBnWC5VXrxFuvToMLDIjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}