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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d64399b84874c941d50e176e2a60284f2e69feaea12e2f43fdcb79e40e59abd' 
  AND token = '/JMKtf0Nik329KmlXlkj+leSiB0c7aPWnaxHGvCCSwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}