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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c680d897d6b93a92ea2e49eddc54bbeef71b838ead5d14da09e3a2ec2ed601d5' 
  AND token = 'XqDPEf1q0xZt83En24t8Q6d33fp/nPz2Odr/7bBJ/s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}