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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3b6f5faefc8f75f35ea25710bd521ef131d12196a41955a091c4bf32e232d1' 
  AND token = '9rzOZRPOviV2tI2y6huHLODuBUjwoOxEb9+pch4Z9rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}