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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b166f8fde91cbb6f202a75394d3978277b3a9ff087f9df26157e15527b3bcf' 
  AND token = 'aqalUGwuSl536LBeib5pZ9KX8knkT0bpeK+zGDgr5us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}