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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f22a0e48e41eb87665685b915e7b9c14987c9474d211483d01c1daeff623d5' 
  AND token = 'EEyPDiPx3/xz0v8I3PIgFmlwwH1VLxBGZW6kdc0cBbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}