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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a78b2649a4ac9acda5f822111d1b838c651751fb89184c3c3c2eeb56657d94b' 
  AND token = '8PWBxqI0EsfF7DSVPBfAR1/4LJOymXDHIanTSFAY7uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}