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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc1020a2825a4be96236fe2b78bc8868ff2347b0054d504012fa651e145f281' 
  AND token = 'u2aM3T96chzUDNxCEMu+F1ipx8KogoMI0Y52le/voJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}