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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80711a349426491492a8e9872673b65a453cd7ae6eb753731a02573c3698ac98' 
  AND token = '4w6i5I/WKhVQ5Tjsvy3uOyNKdlj0DJMTR+ckKQEzRN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}