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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66395172590130b2d1d8ece4d53f9b0245d657f82494eba00bc9ea9e53b592e2' 
  AND token = 'yQyIPvs2iww+sbX/6Oa+R1sjmHD3ijK1kXQ+oowqvYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}