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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a9e2540dd40e66d92b30a2cecf6bad91e286a833e6ec2d6fc9f927be76e943' 
  AND token = 'RwRnJvFRAxvtz1MWh6e9ZO5jb4axm+ciC8zwODlfwoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}