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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35aed6003da0684974f5374233cb52a9f3d5a5d7a5a0843c9a283bf453fbd619' 
  AND token = 'JNLMlfmsvyVtDLV1BZAhE2NwotyWxQcrKSJohNsMz3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}