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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05dbb698980645e8830106b6b88548aeef0cd1e6c2ca000582efea107380bb09' 
  AND token = 'Z2tI924o0aHAMDMBhmwdpMv2AfYx4sEgLL8F33sBtBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}