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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227fcd84d765e2625a270076a43e1726f0e28eb3fe34692735638f55c32ca64d' 
  AND token = 'gIovQFmZ8OZk+1j7yiK2t9/OLPLGF3tKwe7T+k7abnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}