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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5759945c0ac428e907f2fc4d194b1e9099c2e5f01b7c6c6fcc7b1fa1e653658' 
  AND token = 'IKbDkn5WAP6/Vfiec+rBmj5CbqBaxtM9Dxogc5pvV4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}