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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d685d33dcfb0340c17af0dd3c70e0e704c45901294d1439e11d28a3bf280ac6' 
  AND token = '3jzNlgRYOyhjP9onhsufCbpI+WbF2XMbOKzEj8zesdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}