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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bb8e94e5101ea59533acf55f78681f92feb1745640bb186d7a2c4e6c5833ff' 
  AND token = 'edWngzbdDN+SjxLksr7e0LN+eFFH6uyy+EM1G+iGZ6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}