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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a153d7225569e2d37ed1ecbaa5526d1dea707b3aa31045f95e2bf663d40144d5' 
  AND token = '33HhR/TdomqncfUED/yia/0Vkw0zfGawnf+sEo8Itdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}