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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0f7ec0b8f5582d03b015a5f918ae5eb7f0229b14c755f6396659b0a22febea' 
  AND token = 'YoDCyF38aX/paaGn8QxJmWnCeq2AARtO4qUFW4yFygo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}