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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc2432c9761710d8cce638bb2be9348258b152190eec4c2b3896eda286fbd04' 
  AND token = '8YjO3xWwgxX5p+FAHXoH120zMwAIWgCRS6SpJFyO7N4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}