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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8b3661888c9968f0cae4dc6b4214e588353e4564995e6269bc8c4ac295a91d' 
  AND token = 'D/VxA22PzD179HBkGh+ZUzEk1akKTNYFAZd8k+5I0nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}