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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0f8440e2ac1a63790467c8eb31929b558131f476e7e15c0f79d5c8a5d5da2b' 
  AND token = '3yIIYYbn7X7PObK2xp7XkhQAd0WuHaY8LtJf+OnKCvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}