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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6e0ef5a54551085c4613f42be53655c005940441a264c12696a25368615fae' 
  AND token = 'ZyopUpWtk4syPips1kZ62Uryj85YskKgRyCMGMdCg/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}