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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ed6e679d66e3661adf82f8a35424fd9b88a24b790cae0d6479b2bd8aea673f' 
  AND token = 'auRV/CRAu7gHSZodRm4PT9P9jaov3anI/hlHXWPrjT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}