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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fec64eb514a02abb4ac55562d9b27216e6592c595b6a1b1af76421f638ac375d' 
  AND token = 'RGneT2V7NO9HczGe4GknK4TXnxzI6G5xGqZYg8bYOk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}