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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b55fdc4877a147415b034c9650f5c995b9931c9135b691f5b8397dd9c700c1f' 
  AND token = 'd9JcKoDqj7/NqRpRXSCsVvpYaO0O1bsOstt9dL/lXmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}