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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ede88999d591514773a93011052bdae091c7cdf38ed4c4e39dc0120b861f7d' 
  AND token = 'mlAJlHAFCd2mfkdZz7CIm6lYR3rRzcRDvtgM5Nl+j1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}