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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542087baac5adb240bb9f2e8bbcfbf76b94b42b97cc8e660d8bc3c097c2e806d' 
  AND token = 'WQlOiqAGHjLf8v4cDPC86T4R7SEwMYP/8o8jt0SgN5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}