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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5b932d343e125f9276a2ba98accc48d78e8eec3f978a0a105377f285b0367f' 
  AND token = '+a9n+lespK8QLuJ0DIqvSTLgDPKgDM5bqaMfVdtBBco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}