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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2860e15c5d471932512687815051424a88c47e6b9682d04ee8e2fdcff564c8e7' 
  AND token = 'SUof7x1qwtGup8o0yHh+5BCc4Jq2nWuR6fdyXH2OvaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}