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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ed1a026d3ae9d541d6be1fba97538d2f4e7b59c39c325d3d31afb3f64a2699' 
  AND token = 'VGmMsKcmy74EW7sxs2+Ss0V1HodHPC5Alrf7L39O0+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}