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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3882cad00c2a0099eb5fff6e902afd63829637bf9ca2d177f169f9f09bb50d1' 
  AND token = 'ygA3vkIz0OjBZNzn//rs74GRUbtVSyEJKCZ8COnIzgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}