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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604f509c9b6b106c54a61a69f608a4113da286d03b493d179dd2d1d6439a9323' 
  AND token = 'SsEklPwUbVmB8LtAPsTdwMAmgOliDNickrFGL7gRI7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}