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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ecaf43ef5b30c47e7f1f6b2063fe3c88236a139b491dc8633f83f778a5d730b' 
  AND token = 'jpqtb8XhXNAUU+u9SKEZymaba8aJoy1+VBupAD0qBl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}