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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c13279432d95ce672d0c547239fb7f8d5aafcd274c8c0bfd66883eeff4ff4c8' 
  AND token = 'MZQNeRL44Q4XXM0KUKceanJ67RxVOlUtvGIqIR8RSpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}