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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e103718eadf655a26aac48f7ac13d2dadf02e3ad235ed053647948598a06a18' 
  AND token = 'hxcqW3K7lIX/SMuqUNVjuS5lOzhd/afERNxqxWo8Ags=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}