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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da206e4dfb4ac2d4b2a396fe723ef4f240b42c0f7dfd7866ab0a4edfc405f099' 
  AND token = 'CQzZxQ/oTh4hy+xnmBEM6cSMPnNfpaoDIml///8wPWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}