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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e565946fb7f446703ad5345ff4345ef4296d9bee964c611007314360b0f68f1b' 
  AND token = 'NPqYnkSl+I/Yprq0ZpFEp/4mChMXCEu2Ho4hH3ktmhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}