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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a129199f0f2db71e9e9723b29e60e7b2ccf2ce4fd279abdf76f019f15ea2a2' 
  AND token = 'aikfFDcvxEFT4HspxzHrv3wjhBFxelmLiLLJFmUn3Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}